The Department of Peptide-based Immunotherapy, led by Prof. Dr. Juliane Walz at the University and University Hospital Tübingen, focuses on cutting-edge peptide-based immunotherapies to treat cancer and infectious diseases. The team works on multi-omics tools to identify tumor-associated and viral antigens and translate these findings into clinical trials, particularly for vaccine development. We are seeking a highly skilled Bioinformatician to join our bioinformatics group and contribute to developing in-house and publicly available pipelines. Your work will center on mass spectrometry-based immunopeptidomics and the characterization of tumor-associated antigens in both hematological and non-hematological cancers.

Your Tasks:

• Contribute to the discovery of tumor-specific antigens for peptide vaccinations and T-cell immunotherapy
• Enhance and optimize openly accessible data processing pipelines to support mass-spectrometry immunopeptidomics
• Develop novel data analysis workflows and visualization tools for MS-derived immunopeptidomics from in-house datasets
• Integrate proteomics and NGS data into multi-omics analyses

Your profile:

• MSc or PhD in Bioinformatics, Biotechnology, or a related Life Science field
• Hands-on experience with Python and R programming
• Familiarity with Nextflow and nf-core pipelines is a strong plus
• Expertise in high-performance computing (HPC), cloud computing and workflow systems is desirable
• In-depth knowledge of statistics and multivariate data analysis is beneficial
• Excellent communication skills in German and English
• A collaborative and team-oriented mindset.

Further information:

• Join an interdisciplinary, international team at the intersection of translational cancer research and bioinformatics
• Opportunities to contribute to impactful research in cancer immunotherapy and vaccine development
• Access to state-of-the-art computing facilities, including training in Nextflow, HPC, and FAIR data practices
• Professional development and training opportunities in cutting-edge bioinformatics technologies

We offer remuneration in accordance with TV-L (collective wage agreement for the Public Service of the German Federal States), severely handicapped persons with equal qualifications are given preferential consideration. Interview expenses are not covered. Please note the applicable vaccination regulations.