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Karriere
am Klinikum & Medizinischer Fakultät

PhD in Structural Biology of Inflammation (f/m/d)

University Hospital Tübingen, Department of Medical Oncology and Pneumology, index number 6004

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Part-time
65 %
Limited:
1,5 years, extension expected
Start of work:
01.05.2025
Application deadline:
27.04.2025

  • Large-scale recombinant protein expression and numerous purification techniques
  • Protein biochemistry (SDS-PAGE, Western-Blotting, fluorescent and activity assays, etc.)
  • Cryo-EM workflow (cryo-EM grid preparation and screening, data collection and processing, model building, etc.)
  • Cell culture work and cell-based assays (stable cell line generation, viability assays, immunocytofluorescence)
  • Scientific writing and presentation

  • Diploma or Master’s degree (or equivalent) in molecular biology, biochemistry, life sciences or a related discipline
  • Hands-on experience in molecular/cellular biology, recombinant protein production and protein biochemistry is desirable
  • Attention to details, responsibility and creativity
  • Fluency in English (written and spoken)
  • High levels of self-motivation and ability to work both independently, as well as in a team
  • Excellent organization and communication skills
  • Strong interest in structural biology and immunity

Benefits

  • We are a young group working on exciting projects in a highly dynamic, relevant and rapidly developing field.
  • We are looking for like-minded to do excellent science in a vibrant and collaborative atmosphere at one of the top universities in Germany
  •  Application is open now

The University Hospital of Tübingen is a leading center of German university medicine. Every year, around 75,000 inpatients and around 380,000 outpatients are treated. With around 10,600 employees, it is the largest employer in the region. The quality of patient care is certified with the KTQ seal of approval.

Inflammation is the first line defense protecting out bodies against various infections and damages. However, dysregulated due to mutations, environmental factors or lifestyle, inflammation does more bad than good. Indeed, chronic inflammation stands behind such pathologies as diabetes, cardiovascular diseases, neurodegeneration, cancer and many other diseases of the modern-day society. The HYPERLINK "https://www.andreevalab.com/" Andreeva lab (www.andreevalab.com) focuses on structural and functional aspects of inflammatory pathways underlying these pathologies. By using a combination of structural, biochemical and cell-based approaches we aim to comprehensively explain inflammatory pathways from molecular to cellular level, which is crucial for clinical applications and development of novel anti-inflammatory treatments, as well as next generation cancer diagnostics and therapeutics, which are the main goal of the iFIT Cluster of Excellence „Image Guided and Functionally Instructed Tumor Therapies (iFIT)“ consortium, which we are part of.

 

Further reading:

www.cell.com/cell/fulltext/S0092-8674(21)01326-X

www.nature.com/articles/nature23890

www.nature.com/articles/s41586-019-1295-z

Dr. Liudmila Andreeva
07071 29-86773

Dr. Liudmila Andreeva
Index number: 6004
Please send your application forms including a short cover letter (max. 1 A4), a CV, transcripts and certificates of MSc and BSc degrees, as well as contact details for 1-2 references via e-mail (single PDF file) to liudmila.andreeva@med.uni-tuebingen.de
Both German and international applications are encouraged. Applications will be reviewed on an ongoing basis and interviews scheduled accordingly.


Application deadline: 27.04.2025
We offer remuneration in accordance with TV-L (collective wage agreement for the Public Service of the German Federal States), severely handicapped persons with equal qualifications are given preferential consideration. Interview expenses are not covered. Please note the applicable vaccination regulations.
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